Coeliac Disease 

Support, Diagnosis and Management

Coeliac disease is a serious autoimmune condition that causes the immune system to react abnormally to gluten, a protein found in wheat, barley and rye. When someone with coeliac disease eats gluten, the immune system attacks the lining of the small intestine, damaging the tiny villi responsible for absorbing nutrients from food.  

Without treatment, this gut health condition can lead to nutritional deficiencies, digestive symptoms, fatigue, osteoporosis and other long-term health complications. The good news is that most people can successfully manage the condition through a strict lifelong gluten-free diet.


What Is Coeliac Disease? 

It is important to understand that coeliac disease is an autoimmune condition . It is not a food allergy or food intolerance. When someone with coeliac disease consumes gluten, their immune system mistakenly attacks the lining of the small intestine. This damages the villi, reducing the body’s ability to absorb essential nutrients.  Gluten is found in: 

  • Wheat 
  • Barley 
  • Rye 
  • Foods made using these grains, including bread, pasta, cereals, cakes, biscuits, and many processed foods  

How Common Is Coeliac Disease? 

Coeliac disease affects approximately 1 in 100 people in the UK. However, many cases remain undiagnosed, meaning hundreds of thousands of people may be living with symptoms without knowing the cause.  Research suggests that only around a third of people living with the disease have received a formal diagnosis.


Symptoms of Coeliac Disease 

Symptoms vary considerably from person to person, with some individuals experiencing severe digestive symptoms, while others have few or no symptoms at all. Early signs of coeliac disease can include the following common digestive symptoms: 

  • Chronic diarrhoea 
  • Bloating 
  • Excessive wind 
  • Stomach pain 
  • Indigestion 
  • Constipation 
  • Nausea and vomiting 
  • Bulky, greasy or foul-smelling stools  

Symptoms Outside the Digestive System 

Coeliac disease can affect many parts of the body, with common non-digestive symptoms including: 

  • Fatigue 
  • Iron deficiency anaemia 
  • Unexpected weight loss 
  • Brain fog 
  • Mouth ulcers 
  • Headaches 
  • Joint pain 
  • Peripheral neuropathy (tingling or numbness) 
  • Fertility problems 
  • Osteoporosis 
  • Skin rash known as dermatitis herpetiformis  

Symptoms in Children 

Children with untreated coeliac disease may experience: 

  • Failure to thrive 
  • Delayed growth 
  • Short stature 
  • Delayed puberty 
  • Behavioural changes 
  • Dental enamel defects 
  • Weight loss or poor weight gain  

What Causes Coeliac Disease? 

The exact cause is not fully understood. Experts believe it develops through a combination of: 

  • Genetic predisposition 
  • Immune system dysfunction 
  • Environmental triggers 
  • Gluten exposure 
  • Family history of coeliac disease  

If a parent, sibling, or child has coeliac disease, the risk of developing the condition is significantly higher.  


How Is Coeliac Disease Diagnosed? 

Diagnosis usually begins with a blood test that looks for specific antibodies associated with coeliac disease. If results suggest coeliac disease, a specialist may recommend an endoscopy and biopsy of the small intestine to confirm the diagnosis.  

Important 

Do not start a gluten-free diet before testing is completed, as this can affect the accuracy of diagnostic results.  


Treatment for Coeliac Disease 

There is currently no cure, but symptoms and intestinal damage can usually be controlled through a strict gluten-free diet.  

Gluten-Free Diet 

People with coeliac disease must avoid all sources of gluten for life. 

This includes: 

  • Wheat 
  • Barley 
  • Rye 
  • Most conventional bread 
  • Standard pasta 
  • Many breakfast cereals 
  • Certain sauces and processed foods  

Naturally gluten-free foods include: 

  • Meat 
  • Fish 
  • Eggs 
  • Fruit 
  • Vegetables 
  • Rice 
  • Potatoes 
  • Dairy products 
  • Gluten-free grains and alternatives  

Most people notice significant symptom improvement within weeks of adopting a strict gluten-free diet. 


Living with Coeliac Disease 

A diagnosis of coeliac disease requires lifelong dietary management, but many people go on to live healthy, active lives once gluten is removed from their diet.  Helpful strategies include: 

  • Working with a specialist dietitian 
  • Learning to read food labels 
  • Preventing cross-contamination 
  • Planning meals when travelling 
  • Joining support organisations such as Coeliac UK 
  • Attending regular medical reviews  

Potential Complications of Untreated Coeliac Disease 

If left untreated, coeliac disease may increase the risk of: 

  • Osteoporosis 
  • Malnutrition 
  • Iron deficiency anaemia 
  • Fertility issues 
  • Neurological complications 
  • Certain cancers 
  • Ongoing intestinal damage  

Early diagnosis and following a strict diet can significantly reduce these risks.

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When should I get tested for coeliac disease?

You should speak to a healthcare professional if you experience chronic digestive symptoms, unexplained fatigue, iron deficiency anaemia, weight loss, fertility issues, or have a family history of coeliac disease.  

Is coeliac disease the same as gluten intolerance?

No. Coeliac disease is an autoimmune condition. Gluten intolerance or non-coeliac gluten sensitivity does not cause the same immune-mediated intestinal damage.  

Can children outgrow coeliac disease?

No. Coeliac disease is a lifelong autoimmune condition and is not outgrown, although symptoms can often be controlled with a gluten-free diet.  

Is there a cure for coeliac disease?

There is currently no cure. A lifelong gluten-free diet remains the only effective treatment.  

What happens if coeliac disease is left untreated?

Untreated coeliac disease can lead to malnutrition, osteoporosis, anaemia, fertility issues, neurological problems and increased risk of certain cancers.  

How long does it take to feel better after going gluten free?

Many people notice symptom improvement within weeks, although complete intestinal healing can take months or years depending on age and disease severity.  

Can coeliac disease cause skin problems?

Yes. Some people develop dermatitis herpetiformis, an intensely itchy blistering skin rash associated with coeliac disease.  

Can coeliac disease cause fatigue?

Yes. Fatigue is one of the most common symptoms and often results from nutrient deficiencies caused by poor absorption.  

Can I eat oats if I have coeliac disease?

Some people with coeliac disease can tolerate certified gluten-free oats, but medical advice should always be sought before introducing them into the diet.  

What foods should people with coeliac disease avoid?

People with coeliac disease should avoid foods containing wheat, barley, rye and any products derived from these grains unless certified gluten free.  

Is coeliac disease hereditary?

Yes. Having a close family member with coeliac disease increases your risk of developing the condition.  

Can coeliac disease develop later in life?

Yes. Coeliac disease can develop at any age, including adulthood, even in people who have previously tolerated gluten without issues.  

What are the first signs of coeliac disease?

Early symptoms may include bloating, diarrhoea, stomach pain, fatigue, anaemia, unexplained weight loss, and nutritional deficiencies.  

Is coeliac disease an allergy?

No. Coeliac disease is an autoimmune disease rather than a food allergy or intolerance.  

What is coeliac disease?

Coeliac disease is an autoimmune condition where the body’s immune system reacts to gluten and damages the small intestine.  

To learn more about how one of our Coeliac Disease specialists can support you, visit our Digestive Health Treatments page.